>>> a = set('abcthabcjwethddda')
>>> a
set(['a', 'c', 'b', 'e', 'd', 'h', 'j', 't', 'w'])

>>> a = set('abracadabra')
>>> b = set('alacazam')
>>> a                                  # unique letters in a
set(['a', 'r', 'b', 'c', 'd'])
>>> a - b                              # letters in a but not in b
set(['r', 'd', 'b'])
>>> a | b                              # letters in either a or b
set(['a', 'c', 'r', 'd', 'b', 'm', 'z', 'l'])
>>> a & b                              # letters in both a and b
set(['a', 'c'])
>>> a ^ b                              # letters in a or b but not both
set(['r', 'd', 'b', 'm', 'z', 'l'])

>>> a
set(['a', 'c', 'b', 'e', 'd', 'h', 'j', 'q', 't', 'w'])
>>> a.add('p')
>>> a
set(['a', 'c', 'b', 'e', 'd', 'h', 'j', 'q', 'p', 't', 'w'])